cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53

Autophagy is important in regulating the balance between cell death and survival, with the tumor suppressor p53 as one of the key components in this interplay. We have previously utilized an in vitro model of the most common form of childhood cancer, B cell precursor acute lymphoblastic leukemia (BC...

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Vydáno v:Oncotarget
Hlavní autoři: Skah, Seham, Richartz, Nina, Duthil, Eva, Gilljam, Karin M., Bindesbøll, Christian, Naderi, Elin Hallan, Eriksen, Agnete B., Ruud, Ellen, Dirdal, Marta M., Simonsen, Anne, Blomhoff, Heidi Kiil
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084393/
https://ncbi.nlm.nih.gov/pubmed/30100998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25758
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