cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53

Autophagy is important in regulating the balance between cell death and survival, with the tumor suppressor p53 as one of the key components in this interplay. We have previously utilized an in vitro model of the most common form of childhood cancer, B cell precursor acute lymphoblastic leukemia (BC...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Skah, Seham, Richartz, Nina, Duthil, Eva, Gilljam, Karin M., Bindesbøll, Christian, Naderi, Elin Hallan, Eriksen, Agnete B., Ruud, Ellen, Dirdal, Marta M., Simonsen, Anne, Blomhoff, Heidi Kiil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084393/
https://ncbi.nlm.nih.gov/pubmed/30100998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25758
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