cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53

Autophagy is important in regulating the balance between cell death and survival, with the tumor suppressor p53 as one of the key components in this interplay. We have previously utilized an in vitro model of the most common form of childhood cancer, B cell precursor acute lymphoblastic leukemia (BC...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Skah, Seham, Richartz, Nina, Duthil, Eva, Gilljam, Karin M., Bindesbøll, Christian, Naderi, Elin Hallan, Eriksen, Agnete B., Ruud, Ellen, Dirdal, Marta M., Simonsen, Anne, Blomhoff, Heidi Kiil
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084393/
https://ncbi.nlm.nih.gov/pubmed/30100998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25758
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