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Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA
BACKGROUND: APOBEC1 (A1) enzymes are cytidine deaminases involved in RNA editing. In addition to this activity, a few A1 enzymes have been shown to be active on single stranded DNA. As two human ssDNA cytidine deaminases APOBEC3A (A3A), APOBEC3B (A3B) and related enzymes across the spectrum of place...
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| Publicado en: | BMC Genomics |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6854741/ https://ncbi.nlm.nih.gov/pubmed/31726973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6216-x |
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