Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA

BACKGROUND: APOBEC1 (A1) enzymes are cytidine deaminases involved in RNA editing. In addition to this activity, a few A1 enzymes have been shown to be active on single stranded DNA. As two human ssDNA cytidine deaminases APOBEC3A (A3A), APOBEC3B (A3B) and related enzymes across the spectrum of place...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Caval, Vincent, Jiao, Wenjuan, Berry, Noémie, Khalfi, Pierre, Pitré, Emmanuelle, Thiers, Valérie, Vartanian, Jean-Pierre, Wain-Hobson, Simon, Suspène, Rodolphe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854741/
https://ncbi.nlm.nih.gov/pubmed/31726973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6216-x
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