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OncodriveCLUSTL: a sequence-based clustering method to identify cancer drivers

MOTIVATION: Identification of the genomic alterations driving tumorigenesis is one of the main goals in oncogenomics research. Given the evolutionary principles of cancer development, computational methods that detect signals of positive selection in the pattern of tumor mutations have been effectiv...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Arnedo-Pac, Claudia, Mularoni, Loris, Muiños, Ferran, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853674/
https://ncbi.nlm.nih.gov/pubmed/31228182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz501
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