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OncodriveCLUSTL: a sequence-based clustering method to identify cancer drivers

MOTIVATION: Identification of the genomic alterations driving tumorigenesis is one of the main goals in oncogenomics research. Given the evolutionary principles of cancer development, computational methods that detect signals of positive selection in the pattern of tumor mutations have been effectiv...

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Bibliografiska uppgifter
I publikationen:Bioinformatics
Huvudupphovsmän: Arnedo-Pac, Claudia, Mularoni, Loris, Muiños, Ferran, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853674/
https://ncbi.nlm.nih.gov/pubmed/31228182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz501
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