OncodriveCLUSTL: a sequence-based clustering method to identify cancer drivers

MOTIVATION: Identification of the genomic alterations driving tumorigenesis is one of the main goals in oncogenomics research. Given the evolutionary principles of cancer development, computational methods that detect signals of positive selection in the pattern of tumor mutations have been effectiv...

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Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Arnedo-Pac, Claudia, Mularoni, Loris, Muiños, Ferran, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Applications Notes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853674/
https://ncbi.nlm.nih.gov/pubmed/31228182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz501
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