Wordt geladen...

Reduced mutation rate in exons due to differential mismatch repair

While recent studies have revealed higher than anticipated heterogeneity of mutation rate across genomic regions, mutations in exons and introns are assumed to be generated at the same rate. Here we find fewer somatic mutations in exons than expected based on their sequence content, and demonstrate...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Genet
Hoofdauteurs: Frigola, Joan, Sabarinathan, Radhakrishnan, Mularoni, Loris, Muiños, Ferran, Gonzalez-Perez, Abel, López-Bigas, Núria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712219/
https://ncbi.nlm.nih.gov/pubmed/29106418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3991
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!