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Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites

An abnormally high rate of UV-light related mutations appears at transcription factor binding sites (TFBS) across melanomas. The binding of transcription factors (TFs) to the DNA impairs the repair of UV-induced lesions and certain TFs have been shown to increase the rate of generation of these lesi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Frigola, Joan, Sabarinathan, Radhakrishnan, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826277/
https://ncbi.nlm.nih.gov/pubmed/33347579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1219
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