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Macrophage activation by a substituted pyrimido[5,4-b]indole increases anti-cancer activity

Immunotherapy has become a promising new approach for cancer treatment due to the immune system’s ability to remove tumors in a safe and specific manner. Many tumors express anti-inflammatory factors that deactivate the local immune response or recruit peripheral macrophages into pro-tumor roles. Be...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacol Res
Hauptverfasser: Hardie, Joseph, Mas-Rosario, Javier A., Ha, Siyoung, Rizzo, Erik M., Farkas, Michelle E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849472/
https://ncbi.nlm.nih.gov/pubmed/31518642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2019.104452
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