PDCT-16. A PHASE I STUDY OF SUBEROYLANILIDE HYDROXAMIC ACID (SAHA) WITH TEMSIROLIMUS IN CHILDREN WITH NEWLY DIAGNOSED OR PROGRESSIVE DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

Diffuse intrinsic pontine glioma (DIPG) in children remains essentially incurable with a median survival of 12 months. Radiation therapy is currently the standard treatment modality. To date chemotherapy or biologic agents have had no meaningful increase in survival. Data from biopsied DIPG showed t...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Khatua, Soumen, Chandra, Joya, Gopalakrishnan, Vidya, Ketonen, Leena, Johnson, Michael, Sandberg, David, Fuller, Greg, Morrell, Miriam, Meador, Heather, Bolton, Krystal, Butterworth, Ginger, Mukheef, Farah, Sadighi, Zsila, Zaky, Wafik
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Pediatric Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847573/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.776
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