PDCT-16. A PHASE I STUDY OF SUBEROYLANILIDE HYDROXAMIC ACID (SAHA) WITH TEMSIROLIMUS IN CHILDREN WITH NEWLY DIAGNOSED OR PROGRESSIVE DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

Diffuse intrinsic pontine glioma (DIPG) in children remains essentially incurable with a median survival of 12 months. Radiation therapy is currently the standard treatment modality. To date chemotherapy or biologic agents have had no meaningful increase in survival. Data from biopsied DIPG showed t...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Khatua, Soumen, Chandra, Joya, Gopalakrishnan, Vidya, Ketonen, Leena, Johnson, Michael, Sandberg, David, Fuller, Greg, Morrell, Miriam, Meador, Heather, Bolton, Krystal, Butterworth, Ginger, Mukheef, Farah, Sadighi, Zsila, Zaky, Wafik
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Pediatric Clinical Trials
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847573/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.776
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