Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition

The complex between Trm7 and Trm734 (Trm7–Trm734) from Saccharomyces cerevisiae catalyzes 2′-O-methylation at position 34 in tRNA. We report biochemical and structural studies of the Trm7–Trm734 complex. Purified recombinant Trm7–Trm734 preferentially methylates tRNA(Phe) transcript variants possess...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Hirata, Akira, Okada, Keisuke, Yoshii, Kazuaki, Shiraishi, Hiroyuki, Saijo, Shinya, Yonezawa, Kento, Shimizu, Nobutaka, Hori, Hiroyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Structural Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847430/
https://ncbi.nlm.nih.gov/pubmed/31586407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz856
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi