The tRNA Recognition Mechanism of Folate/FAD-dependent tRNA Methyltransferase (TrmFO)

The conserved U54 in tRNA is often modified to 5-methyluridine (m(5)U) and forms a reverse Hoogsteen base pair with A58 that stabilizes the L-shaped tRNA structure. In Gram-positive and some Gram-negative eubacteria, m(5)U54 is produced by folate/FAD-dependent tRNA (m(5)U54) methyltransferase (TrmFO...

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Autors principals: Yamagami, Ryota, Yamashita, Koki, Nishimasu, Hiroshi, Tomikawa, Chie, Ochi, Anna, Iwashita, Chikako, Hirata, Akira, Ishitani, Ryuichiro, Nureki, Osamu, Hori, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522250/
https://ncbi.nlm.nih.gov/pubmed/23095745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390112
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