Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition

The complex between Trm7 and Trm734 (Trm7–Trm734) from Saccharomyces cerevisiae catalyzes 2′-O-methylation at position 34 in tRNA. We report biochemical and structural studies of the Trm7–Trm734 complex. Purified recombinant Trm7–Trm734 preferentially methylates tRNA(Phe) transcript variants possess...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hirata, Akira, Okada, Keisuke, Yoshii, Kazuaki, Shiraishi, Hiroyuki, Saijo, Shinya, Yonezawa, Kento, Shimizu, Nobutaka, Hori, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847430/
https://ncbi.nlm.nih.gov/pubmed/31586407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz856
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados