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Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition
The complex between Trm7 and Trm734 (Trm7–Trm734) from Saccharomyces cerevisiae catalyzes 2′-O-methylation at position 34 in tRNA. We report biochemical and structural studies of the Trm7–Trm734 complex. Purified recombinant Trm7–Trm734 preferentially methylates tRNA(Phe) transcript variants possess...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nucleic Acids Res |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6847430/ https://ncbi.nlm.nih.gov/pubmed/31586407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz856 |
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