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Transfer RNA methyltransferases with a SpoU-TrmD (SPOUT) fold and their modified nucleosides in tRNA

The existence of SpoU-TrmD (SPOUT) RNA methyltransferase superfamily was first predicted by bioinformatics. SpoU is the previous name of TrmH, which catalyzes the 2’-O-methylation of ribose of G18 in tRNA; TrmD catalyzes the formation of N(1)-methylguanosine at position 37 in tRNA. Although SpoU (Tr...

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Detalles Bibliográficos
Publicado en:Biomolecules
Autor Principal: Hori, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372735/
https://ncbi.nlm.nih.gov/pubmed/28264529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7010023
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