Characterization of Streptococcus pneumoniae TrmD, a tRNA Methyltransferase Essential for Growth

Down-regulation of expression of trmD, encoding the enzyme tRNA (guanosine-1)-methyltransferase, has shown that this gene is essential for growth of Streptococcus pneumoniae. The S. pneumoniae trmD gene has been isolated and expressed in Escherichia coli by using a His-tagged T7 expression vector. R...

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Detalhes bibliográficos
Main Authors: O'Dwyer, Karen, Watts, Joseph M., Biswas, Sanjoy, Ambrad, Jennifer, Barber, Michael, Brulé, Hervé, Petit, Chantal, Holmes, David J., Zalacain, Magdalena, Holmes, Walter M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Enzymes and Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC412112/
https://ncbi.nlm.nih.gov/pubmed/15060037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.8.2346-2354.2004
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