DRES-12. QUANTIFYING INDIVIDUALIZED ABT-414 SENSITIVITY AND BLOOD-BRAIN BARRIER PENETRANCE FROM SERIAL IMAGING OF PATIENT-DERIVED XENOGRAFTS MODELS OF GLIOBLASTOMA

INTRODUCTION: Glioblastoma (GBM) is an aggressive primary brain tumor, known for its poor prognosis. Due to its diffuse invasiveness into normal-appearing brain, localized treatments such as surgical resection and radiotherapy are typically supplemented with chemotherapy. However, to reach invading...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Urcuyo, Javier, Christine Massey, Susan, Marin, Bianca-Maria, Sarkaria, Jann, Swanson, Kristin
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Drug Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847361/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.299
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