Nalaganje...
DDIS-01. THE ANTIBODY-DRUG CONJUGATE ABT-414 DEMONSTRATES SINGLE-AGENT ANTI-CANCER ACTIVITY ACROSS A PANEL OF GBM PATIENT-DERIVED XENOGRAFTS
ABT-414 is a novel antibody-drug conjugate (ADC) of monomethyl auristatin F (MMAF), a microtubule destabilizing agent, and an anti-EGFR antibody (ABT-806). ABT-414 has demonstrated promising efficacy in clinical trials against newly diagnosed and recurrent glioblastoma (GBM), but little is known abo...
Shranjeno v:
| izdano v: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217207/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.280 |
| Oznake: |
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