PM-19 DEVELOPMENT OF A PANEL OF PATIENT-DERIVED XENOGRAFT (PDX) MODELS FROM BRAIN METASTASES

BACKGROUND: Most common models of brain metastases are developed from established cell lines selected for brain tropism. We hypothesized that PDX models derived from brain metastases would maintain brain tropism and more faithfully maintain features of primary brain metastases. METHODS: Resected bra...

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Autores principales: Sarkaria, Jann, Ma, Daniel, Schroeder, Mark, Carlson, Brett, Giannini, Caterina, Parney, Ian
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218480/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou268.19
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