TMOD-11. IMAGING BASED INVASION METRIC PREDICTIVE OF RESPONSE TO ABT414 IN ORTHOTOPIC EGFRviii AMPLIFIED PATIENT DERIVED XENOGRAFTS

BACKGROUND: Failed trials involving targeted therapies face a daunting task of understanding whether the root cause was inadequate targeting, resistance, or insufficient delivery to the tumor. Previous work with a bio-mathematical model has shown the prognostic value of an imaging based invasion met...

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Publicado en:Neuro Oncol
Main Authors: Christine Massey, Susan, Marin, Bianca, Hawkins-Daarud, Andrea, Paulson, Lisa, Kasle, Lauren, Jackson, Pamela, Mladek, Ann, Sarkaria, Jann, Swanson, Kristin
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216554/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1124
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