EXTH-20. HYPERPOLARIZED [2-(13)C] PYRUVATE TO [5-(13)C] GLUTAMATE AS BIOMARKERS OF IDH1 MUTANT GLIOMA RESPONSE TO TEMOZOLOMIDE THERAPY

Low-grade gliomas, driven by mutations in the cytosolic isocitrate dehydrogenase 1 (IDH1) gene, are less aggressive than primary glioblastoma, but nonetheless always recur and ultimately lead to patient death. The treatment of IDH1 mutant patients with Temozolomide (TMZ) improves survival, but there...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Subramani, Elavarasan, Najac, Chloe, Batsios, Georgios, Viswanath, Pavithra, Radoul, Marina, Marie Gillespie, Anne, Pieper, Russell O, Ronen, Sabrina
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847284/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.354
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars