Nalaganje...
CSIG-12. PREX1 LINKS ABERRANT PI 3-KINASE PATHWAY SIGNALING TO MAINTENANCE OF THE NEURAL STEM CELL-LIKE PHENOTYPE OF GLIOBLASTOMA CELLS
Virtually all primary glioblastomas have aberrant activation of the PI 3-kinase pathway through mutational inactivation of tumour suppressors such as PTEN and/or mutational activation of oncogenes. Most glioblastomas also overexpress the Rac guanine nucleotide exchange factor PREX1, which is activat...
Shranjeno v:
| izdano v: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2019
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6847169/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.183 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|