PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion

A defining feature of the brain cancer glioblastoma is its highly invasive nature. When glioblastoma cells are isolated from patients using serum free conditions, they accurately recapitulate this invasive behaviour in animal models. The Rac subclass of Rho GTPases has been shown to promote invasive...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Gont, Alexander, Daneshmand, Manijeh, Woulfe, John, Lavictoire, Sylvie J., Lorimer, Ian A.J .
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352422/
https://ncbi.nlm.nih.gov/pubmed/28051998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14348
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