PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion

A defining feature of the brain cancer glioblastoma is its highly invasive nature. When glioblastoma cells are isolated from patients using serum free conditions, they accurately recapitulate this invasive behaviour in animal models. The Rac subclass of Rho GTPases has been shown to promote invasive...

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Foilsithe in:Oncotarget
Main Authors: Gont, Alexander, Daneshmand, Manijeh, Woulfe, John, Lavictoire, Sylvie J., Lorimer, Ian A.J .
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352422/
https://ncbi.nlm.nih.gov/pubmed/28051998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14348
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