CSIG-07. TARGETING CELL POLARITY PROTEINS FROM THE SCRIBBLE COMPLEX DISRUPTS GLIOBLASTOMA STEM CELL VIABILITY AND INVASION IN NEURAL TISSUE

Despite their molecular heterogeneity, glioblastomas (GBMs) retain a common phenotypical feature, which is their diffuse invasion through neural tissue that makes complete resection impossible. This invasive ability requires changes in cell polarity for the tumor cells to migrate following cues from...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Kundu, Somanath, Nandhu, Mohan, Longo, Sharon, Longo, John, Richardson, Timothy, Chin, Lawrence, Viapiano, Mariano
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Cell Signaling and Signaling Pathways
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846951/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.178
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