CSIG-07. TARGETING CELL POLARITY PROTEINS FROM THE SCRIBBLE COMPLEX DISRUPTS GLIOBLASTOMA STEM CELL VIABILITY AND INVASION IN NEURAL TISSUE

Despite their molecular heterogeneity, glioblastomas (GBMs) retain a common phenotypical feature, which is their diffuse invasion through neural tissue that makes complete resection impossible. This invasive ability requires changes in cell polarity for the tumor cells to migrate following cues from...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kundu, Somanath, Nandhu, Mohan, Longo, Sharon, Longo, John, Richardson, Timothy, Chin, Lawrence, Viapiano, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Cell Signaling and Signaling Pathways
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846951/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.178
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