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IMMU-39. FIRST-IN-KIND T CELLS CARRYING A CHIMERIC ANTIGEN RECEPTOR AGAINST AN EXTRACELLULAR MATRIX PROTEIN TARGET GLIOBLASTOMA CELLS AND SHOW ANTI-TUMOR EFFICACY
Immunotherapies using engineered T lymphocytes expressing chimeric antigen receptors (CAR-T cells) are showing great promise against glioblastoma but are still limited by the escape of antigen-deficient clones and by inefficient latching of the T cells to target cells surrounded by extracellular mat...
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Publicado no: | Neuro Oncol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216372/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.542 |
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