IMMU-39. FIRST-IN-KIND T CELLS CARRYING A CHIMERIC ANTIGEN RECEPTOR AGAINST AN EXTRACELLULAR MATRIX PROTEIN TARGET GLIOBLASTOMA CELLS AND SHOW ANTI-TUMOR EFFICACY

Immunotherapies using engineered T lymphocytes expressing chimeric antigen receptors (CAR-T cells) are showing great promise against glioblastoma but are still limited by the escape of antigen-deficient clones and by inefficient latching of the T cells to target cells surrounded by extracellular mat...

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Publié dans:Neuro Oncol
Auteurs principaux: Sengupta, Sadhak, Nandhu, Mohan, Longo, Sharon, Sengupta, Sudarshana, Longo, John, Sampath, Prakash, Viapiano, Mariano
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216372/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.542
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