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CBMT-47. MODULATION OF NAD PATHWAYS AS A THERAPEUTIC STRATEGY FOR TARGETING IDH MUTANT GLIOMA
BACKGROUND: IDH mutant tumors exhibit an altered metabolic state which may be exploited for use as a novel therapeutic approach. Our previous work has shown the IDH mutant cancer survival is dependent on the biosynthetic enzyme, nicotinamide phosphoribosyltransferase (NAMPT), for the production of n...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6846952/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.169 |
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