Sirtuin activation targets IDH-mutant tumors

BACKGROUND: Isocitrate dehydrogenase (IDH)–mutant tumors exhibit an altered metabolic state and are critically dependent upon nicotinamide adenine dinucleotide (NAD+) for cellular survival. NAD+ steady-state levels can be influenced by both biosynthetic and consumptive processes. Here, we investigat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Miller, Julie J, Fink, Alexandria, Banagis, Jack A, Nagashima, Hiroaki, Subramanian, Megha, Lee, Christine K, Melamed, Lisa, Tummala, Shilpa S, Tateishi, Kensuke, Wakimoto, Hiroaki, Cahill, Daniel P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850026/
https://ncbi.nlm.nih.gov/pubmed/32710757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa180
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados