GENE-40. CHARACTERIZING EPIGENETIC INTRATUMORAL HETEROGENEITY IN GLIOMA USING SINGLE-CELL BISULFITE SEQUENCING

Genetic and epigenetic alterations contribute to the observed intratumoral heterogeneity in adult glioma. Current glioma classification, based on genotype (e.g., IDH1 mutations) and DNA methylation profiles (e.g., glioma CpG Island Methylator Phenotype), can provide clinically relevant tumor subgrou...

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Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Johnson, Kevin C, Anderson, Kevin, Courtois, Elise, Barthel, Floris, Samuels, Michael, Robson, Paul, Bulsara, Ketan, Das, Sunit, Verhaak, Roel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Genetics and Epigenetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846935/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.442
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