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GENE-59. CHARACTERIZING EPIGENETIC INTRATUMORAL HETEROGENEITY IN GLIOMA USING SINGLE-CELL REDUCED REPRESENTATION BISULFITE SEQUENCING

Determining the cellular mechanisms that govern glioma heterogeneity can impact the development of novel therapies, protect patients from side effects of unnecessary treatment, and prevent glioma recurrence. Emerging evidence suggests that molecular subtypes in glioma, based on genotype (e.g., IDH1...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Johnson, Kevin, Tang, Ming, Estécio, Marcos, Robson, Paul, Verhaak, Roel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692730/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.431
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