EPCO-27. GLIOMA SINGLE CELL MULTI-OMIC ANALYSES REVEALS REGULATORS OF PLASTICITY AND ADAPTIVE STRESS RESPONSE

Extensive intra- and intertumoral heterogeneity in glioma contributes to therapeutic resistance and poor patient outcomes. Alterations to DNA methylation (DNAme) modulate epigenetic homeostasis, allowing tumor cells to sample alternative cell states to promote tumorigenesis. However, the epigenetic...

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Vydáno v:Neuro Oncol
Hlavní autoři: Johnson, Kevin, Anderson, Kevin, Courtois, Elise, Barthel, Floris, Varn, Frederick, Luo, Diane, Yi, Eunhee, Kim, Hoon, Estecio, Marcos, Tang, Ming, Navin, Nicholas, Maurya, Rahul, Ngan, Chewyee, Bulsara, Ketan, Samuels, Michael, Das, Sunit, Robson, Paul, Verhaak, Roel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
(Epi)Genetics and Computational Omics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650923/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.306
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