EPCO-27. GLIOMA SINGLE CELL MULTI-OMIC ANALYSES REVEALS REGULATORS OF PLASTICITY AND ADAPTIVE STRESS RESPONSE

Extensive intra- and intertumoral heterogeneity in glioma contributes to therapeutic resistance and poor patient outcomes. Alterations to DNA methylation (DNAme) modulate epigenetic homeostasis, allowing tumor cells to sample alternative cell states to promote tumorigenesis. However, the epigenetic...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Johnson, Kevin, Anderson, Kevin, Courtois, Elise, Barthel, Floris, Varn, Frederick, Luo, Diane, Yi, Eunhee, Kim, Hoon, Estecio, Marcos, Tang, Ming, Navin, Nicholas, Maurya, Rahul, Ngan, Chewyee, Bulsara, Ketan, Samuels, Michael, Das, Sunit, Robson, Paul, Verhaak, Roel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
(Epi)Genetics and Computational Omics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650923/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.306
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