EPCO-15. TUMOR TREATMENT WITH IONIZING RADIATION IS ASSOCIATED WITH A CLINICALLY RELEVANT DELETION SIGNATURE

Diffuse gliomas are highly aggressive brain tumors that invariably relapse despite treatment with chemo- and radiotherapy. Treatment with alkylating chemotherapy can drive tumors to develop a hypermutator phenotype. In contrast, the genomic effects of radiation therapy (RT) remain unknown. We analyz...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Kocakavuk, Emre, Anderson, Kevin, Johnson, Kevin, Varn, Frederick, Amin, Samirkumar, Barthel, Floris, Verhaak, Roel
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
(Epi)Genetics and Computational Omics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651419/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.294
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