EPCO-15. TUMOR TREATMENT WITH IONIZING RADIATION IS ASSOCIATED WITH A CLINICALLY RELEVANT DELETION SIGNATURE

Diffuse gliomas are highly aggressive brain tumors that invariably relapse despite treatment with chemo- and radiotherapy. Treatment with alkylating chemotherapy can drive tumors to develop a hypermutator phenotype. In contrast, the genomic effects of radiation therapy (RT) remain unknown. We analyz...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Kocakavuk, Emre, Anderson, Kevin, Johnson, Kevin, Varn, Frederick, Amin, Samirkumar, Barthel, Floris, Verhaak, Roel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
(Epi)Genetics and Computational Omics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651419/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.294
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky