EPCO-27. GLIOMA SINGLE CELL MULTI-OMIC ANALYSES REVEALS REGULATORS OF PLASTICITY AND ADAPTIVE STRESS RESPONSE

Extensive intra- and intertumoral heterogeneity in glioma contributes to therapeutic resistance and poor patient outcomes. Alterations to DNA methylation (DNAme) modulate epigenetic homeostasis, allowing tumor cells to sample alternative cell states to promote tumorigenesis. However, the epigenetic...

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Johnson, Kevin, Anderson, Kevin, Courtois, Elise, Barthel, Floris, Varn, Frederick, Luo, Diane, Yi, Eunhee, Kim, Hoon, Estecio, Marcos, Tang, Ming, Navin, Nicholas, Maurya, Rahul, Ngan, Chewyee, Bulsara, Ketan, Samuels, Michael, Das, Sunit, Robson, Paul, Verhaak, Roel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
(Epi)Genetics and Computational Omics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650923/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.306
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