EXTH-25. A MECHANICALLY-ENGINEERED SPRAY TO INCREASE BRAIN PENETRATION OF CHEMOTHERAPEUTIC NANOPARTICLES IN THE TREATMENT OF HIGH GRADE GLIOMAS

Design and implementation of innovative local drug delivery systems (DDS) may overcome current limitations in GBM treatment, such as the lack of therapeutic drug concentrations reaching residual GBM cells following surgery. Here we describe a novel DDS which utilises a bespoke mechanically engineere...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: McCrorie, Phoebe, Taresco, Vincenzo, Ritchie, Alison, Clarke, Phillip, Scurr, David, Marlow, Maria, Rahman, Ruman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846913/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.358
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