EXTH-53. TUMOR TREATING FIELDS LEADS TO CHANGES IN MEMBRANE PERMEABILITY AND INCREASED PENETRATION BY ANTI-GLIOMA DRUGS

BACKGROUND: Efforts are underway to uncover novel, unorthodox therapies against glioblastoma (GBM). Tumor treating fields (TTFields) disrupt mitotic spindle formation and stymie proliferation in tumor cells. Combining TTFields with Withaferin A, synergistically inhibited proliferation in GBM. We wis...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Chang, Edwin, Patel, Chirag, Beinat, Corinne, Young, Caroline, Flores, Thomas, Zeng, Yitian, Joubert, Lydia, Arami, Hamed, Natarajan, Arutselvan, Sinclair, Robert, Gambhir, Sanjiv
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847479/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.384
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