Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes

Targeted differentiation of pluripotent stem (PS) cells into myotubes enables in vitro disease modeling of skeletal muscle diseases. Although various protocols achieve myogenic differentiation in vitro, resulting myotubes typically display an embryonic identity. This is a major hurdle for accurately...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Selvaraj, Sridhar, Mondragon-Gonzalez, Ricardo, Xu, Bin, Magli, Alessandro, Kim, Hyunkee, Lainé, Jeanne, Kiley, James, Mckee, Holly, Rinaldi, Fabrizio, Aho, Joy, Tabti, Nacira, Shen, Wei, Perlingeiro, Rita CR
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2019
Konular:
Developmental Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845233/
https://ncbi.nlm.nih.gov/pubmed/31710288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47970
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