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Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes

Targeted differentiation of pluripotent stem (PS) cells into myotubes enables in vitro disease modeling of skeletal muscle diseases. Although various protocols achieve myogenic differentiation in vitro, resulting myotubes typically display an embryonic identity. This is a major hurdle for accurately...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:eLife
Main Authors: Selvaraj, Sridhar, Mondragon-Gonzalez, Ricardo, Xu, Bin, Magli, Alessandro, Kim, Hyunkee, Lainé, Jeanne, Kiley, James, Mckee, Holly, Rinaldi, Fabrizio, Aho, Joy, Tabti, Nacira, Shen, Wei, Perlingeiro, Rita CR
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications, Ltd 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845233/
https://ncbi.nlm.nih.gov/pubmed/31710288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47970
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