Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes

Targeted differentiation of pluripotent stem (PS) cells into myotubes enables in vitro disease modeling of skeletal muscle diseases. Although various protocols achieve myogenic differentiation in vitro, resulting myotubes typically display an embryonic identity. This is a major hurdle for accurately...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Selvaraj, Sridhar, Mondragon-Gonzalez, Ricardo, Xu, Bin, Magli, Alessandro, Kim, Hyunkee, Lainé, Jeanne, Kiley, James, Mckee, Holly, Rinaldi, Fabrizio, Aho, Joy, Tabti, Nacira, Shen, Wei, Perlingeiro, Rita CR
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845233/
https://ncbi.nlm.nih.gov/pubmed/31710288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47970
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