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Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation
Genome-wide association studies (GWAS) and functional genomic analyses have implicated several ITGAM (CD11b) single-nucleotide polymorphisms (SNPs) in the development of SLE and other disorders. ITGAM encodes the α(M) chain of the β(2) integrin Mac-1, a receptor that plays important roles in myeloid...
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| Publicado no: | Mamm Genome |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6842653/ https://ncbi.nlm.nih.gov/pubmed/31673770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-019-09819-y |
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