ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash, and immunologic manifestations in lupus patients with European ancestry

PURPOSE: We hypothesized that the coding variant (R77H), rs1143679, within ITGAM could predict specific clinical manifestations associated with lupus. METHOD: To assess genetic association, 2366 lupus cases and 2931 unaffected controls with European ancestry were analyzed. Lupus patients were coded...

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Detalhes bibliográficos
Main Authors: Kim-Howard, Xana, Maiti, Amit K., Anaya, Juan-Manuel, Bruner, Gail R., Brown, Elizabeth, Merrill, Joan T., Edberg, Jeffrey C., Petri, Michelle A., Reveille, John D., Ramsey-Goldman, Rosalind, Alarcon, Graciela S., Vyse, Timothy J., Gilkeson, Gary, Kimberly, Robert P., James, Judith A., Guthridge, Joel M., Harley, John B., Nath, Swapan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891778/
https://ncbi.nlm.nih.gov/pubmed/19939855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2009.120543
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