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Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples

Human cysteine cathepsins constitute an 11-membered family of proteases responsible for degradation of proteins in cellular endosomal–lysosomal compartments as such, they play important roles in antigen processing, cellular stress signaling, autophagy, and senescence. Moreover, for many years these...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Poreba, Marcin, Groborz, Katarzyna, Vizovisek, Matej, Maruggi, Marco, Turk, Dusan, Turk, Boris, Powis, Garth, Drag, Marcin, Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839509/
https://ncbi.nlm.nih.gov/pubmed/31803426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00997c
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