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Multiplexed probing of proteolytic enzymes using mass cytometry-compatible activity-based probes.
The subset of the proteome that contains enzymes in their catalytically active form can be interrogated by using probes targeted towards individual specific enzymes. A subset of such enzymes are proteases that are frequently studied with activity-based probes, small inhibitors equipped with a detect...
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| Vydáno v: | J Am Chem Soc |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7595764/ https://ncbi.nlm.nih.gov/pubmed/32870676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c06762 |
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