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Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation

Enhancers can regulate the promoters of their target genes over very large genomic distances. It is widely assumed that mechanisms of enhancer action involve the reorganization of three-dimensional chromatin architecture, but this is poorly understood. The predominant model involves physical enhance...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Benabdallah, Nezha S., Williamson, Iain, Illingworth, Robert S., Kane, Lauren, Boyle, Shelagh, Sengupta, Dipta, Grimes, Graeme R., Therizols, Pierre, Bickmore, Wendy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838673/
https://ncbi.nlm.nih.gov/pubmed/31494034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.038
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