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Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization

Although important for gene regulation, most studies of genome organization use either fluorescence in situ hybridization (FISH) or chromosome conformation capture (3C) methods. FISH directly visualizes the spatial relationship of sequences but is usually applied to a few loci at a time. The frequen...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Williamson, Iain, Berlivet, Soizik, Eskeland, Ragnhild, Boyle, Shelagh, Illingworth, Robert S., Paquette, Denis, Dostie, Josée, Bickmore, Wendy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265680/
https://ncbi.nlm.nih.gov/pubmed/25512564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.251694.114
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