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A central role for canonical PRC1 in shaping the 3D nuclear landscape
Polycomb group (PcG) proteins silence gene expression by chemically and physically modifying chromatin. A subset of PcG target loci are compacted and cluster in the nucleus; a conformation that is thought to contribute to gene silencing. However, how these interactions influence gross nuclear organi...
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| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7328521/ https://ncbi.nlm.nih.gov/pubmed/32439634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.336487.120 |
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