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Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation

Enhancers can regulate the promoters of their target genes over very large genomic distances. It is widely assumed that mechanisms of enhancer action involve the reorganization of three-dimensional chromatin architecture, but this is poorly understood. The predominant model involves physical enhance...

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Detalles Bibliográficos
Publicado en:Mol Cell
Main Authors: Benabdallah, Nezha S., Williamson, Iain, Illingworth, Robert S., Kane, Lauren, Boyle, Shelagh, Sengupta, Dipta, Grimes, Graeme R., Therizols, Pierre, Bickmore, Wendy A.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838673/
https://ncbi.nlm.nih.gov/pubmed/31494034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.038
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