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TIP60/KAT5 is required for neuronal viability in hippocampal CA1
Aberrant histone acetylation contributes to age-dependent cognitive decline and neurodegenerative diseases. We analyze the function of lysine acetyltransferase TIP60/KAT5 in neurons of the hippocampus using an inducible mouse model. TIP60-deficiency in the adult forebrain leads within days to extens...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6838100/ https://ncbi.nlm.nih.gov/pubmed/31700011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50927-1 |
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