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KAT–independent gene regulation by Tip60 promotes ESC self-renewal but not pluripotency
Although histone-modifying enzymes are generally assumed to function in a manner dependent on their enzymatic activities, this assumption remains untested for many factors. Here we show the Tip60 (Kat5) lysine acetyltransferase (KAT), which is essential for embryonic stem cell (ESC) self-renewal and...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484067/ https://ncbi.nlm.nih.gov/pubmed/28445719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.04.001 |
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