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Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters

Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. To investigate temporal regulation in this molecular oscillator, we combined mouse genetic approaches and analyses of interactions of key circadian proteins wi...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Petkau, Nikolai, Budak, Harun, Zhou, Xunlei, Oster, Henrik, Eichele, Gregor
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650244/
https://ncbi.nlm.nih.gov/pubmed/31294688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43235
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